› 8jn7

Electron Microscopy
11Å resolution

Cryo-EM structure of the big tail club shape particle of dengue virus serotype 3 strain CH53489 in complex with human antibody DENV-290 Fab at 37 deg C

Released:
DOI: 10.2210/pdb8jn7/pdb
PDB entry 8jn7 coloured by chain, front view.
PDB entry 8jn7 coloured by chain, side view.
PDB entry 8jn7 coloured by chain, top view.
Source organisms:
Entry authors: Fibriansah G, Ng TS, Tan AWK, Shi J, Lok SM
Related structures: EMD-36435

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero 196-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-245862 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Polyprotein (Fragment) Chains: C, E
Molecule details ›
Chains: C, E
Length: 493 amino acids
Theoretical weight: 53.73 KDa
Source organism: dengue virus type 3
Expression system: Aedes albopictus
UniProt:
  • Canonical: Q07019 (Residues: 167-659; Coverage: 75%)
Sequence domains:
Human antibody DENV-290 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 122 amino acids
Theoretical weight: 13.5 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Human antibody DENV-290 light chain Chain: L
Molecule details ›
Chain: L
Length: 113 amino acids
Theoretical weight: 12.38 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 11Å
Relevant EMDB volumes: EMD-36435
Expression systems:
  • Aedes albopictus
  • Homo sapiens

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