› 8jqu

X-ray diffraction
1.8Å resolution

Crystal structure of GppNHp bound GTPase domain of Rab5a from Leishmania donovani

Released:
DOI: 10.2210/pdb8jqu/pdb
PDB entry 8jqu coloured by chain, front view.
PDB entry 8jqu coloured by chain, side view.
PDB entry 8jqu coloured by chain, top view.
Source organism: Leishmania donovani
Entry authors: Pandey D, Zohib M, Pal RK, Biswal BK, Arora A

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-102843 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rab5a Chain: A
Molecule details ›
Chain: A
Length: 175 amino acids
Theoretical weight: 19.24 KDa
Source organism: Leishmania donovani
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: A0A109NYM0 (Residues: 1-195; Coverage: 75%)
Gene name: Rab5a
Sequence domains: Ras family

Ligands and Environments

3 bound ligands:
Ligand EDO 1 x EDO
Ligand GNP 1 x GNP
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: C2
Unit cell:
a: 110.552Å b: 42.266Å c: 37.777Å
α: 90° β: 103.387° γ: 90°
R-values:
R R work R free
0.164 0.162 0.203
Expression system: Escherichia coli BL21

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