› 8juw

Electron Microscopy
3.79Å resolution

Human ATAD2 Walker B mutant-H3/H4K5Q complex, ATP state

Released:
DOI: 10.2210/pdb8juw/pdb
PDB entry 8juw coloured by chain, front view.
PDB entry 8juw coloured by chain, side view.
PDB entry 8juw coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication.
Cho C, Ganser C, Uchihashi T, Kato K, Song JJ
OpenAccess logo Commun Biol 6 993 (2023)
PMID: 37770645
Related structures: EMD-36665

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-274902 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATPase family AAA domain-containing protein 2 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 831 amino acids
Theoretical weight: 93.69 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q6PL18 (Residues: 403-1390; Coverage: 60%)
  • Best match: Q6PL18-2 (Residues: 233-380)
Gene names: ATAD2, L16, PRO2000
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand ADP 1 x ADP
Ligand ATP 5 x ATP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.79Å
Relevant EMDB volumes: EMD-36665
Expression system: Spodoptera frugiperda

Quick links

Citations

1 mention without citation

Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication.
Cho et al. (2023)