› 8jy7

Electron Microscopy
3.2Å resolution

Structure of the TbAQP2 in the apo conformation

Released:
DOI: 10.2210/pdb8jy7/pdb
PDB entry 8jy7 coloured by chain, front view.
PDB entry 8jy7 coloured by chain, side view.
PDB entry 8jy7 coloured by chain, top view.
Source organism: Trypanosoma brucei brucei
Primary publication:
Structural insights into drug transport by an aquaglyceroporin.
Chen W, Zou R, Mei Y, Li J, Xuan Y, Cui B, Zou J, Wang J, Lin S, Zhang Z, Wang C
OpenAccess logo Nat Commun 15 3985 (2024)
PMID: 38734677
Related structures: EMD-36722

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-244873 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aquaglyceroporin-2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 343 amino acids
Theoretical weight: 36.78 KDa
Source organism: Trypanosoma brucei brucei
Expression system: Homo sapiens
UniProt:
  • Canonical: Q6ZXT3 (Residues: 1-312; Coverage: 100%)
Gene name: AQP2
Sequence domains: Major intrinsic protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.2Å
Relevant EMDB volumes: EMD-36722
Expression system: Homo sapiens

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