8k1j

Electron Microscopy
3Å resolution

Human TWIK-related acid-sensitive potassium channel TASK3 at pH 7.4,200 mM KCl

Released:
Source organism: Homo sapiens
Primary publication:
C-type inactivation and proton modulation mechanisms of the TASK3 channel.
Proc Natl Acad Sci U S A 121 e2320345121 (2024)
PMID: 38630723
Related structures: EMD-36793

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-275432 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium channel subfamily K member 9 Chains: A, B
Molecule details ›
Chains: A, B
Length: 275 amino acids
Theoretical weight: 31.17 KDa
Source organism: Homo sapiens
Expression system: eukaryotic plasmids
UniProt:
  • Canonical: Q9NPC2 (Residues: 1-259; Coverage: 69%)
Gene names: KCNK9, TASK3
Sequence domains: Ion channel

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution:
Relevant EMDB volumes: EMD-36793
Expression system: eukaryotic plasmids