› 8k4b

Electron Microscopy
3.9Å resolution

Cryo-EM structure of nucleotide-bound ComA with ZinC ion

Released:
DOI: 10.2210/pdb8k4b/pdb
PDB entry 8k4b coloured by chain, front view.
PDB entry 8k4b coloured by chain, side view.
PDB entry 8k4b coloured by chain, top view.
Source organism: Streptococcus pneumoniae D39
Primary publication:
Structural basis of peptide secretion for Quorum sensing by ComA.
Yu L, Xu X, Chua WZ, Feng H, Ser Z, Shao K, Shi J, Wang Y, Li Z, Sobota RM, Sham LT, Luo M
OpenAccess logo Nat Commun 14 7178 (2023)
PMID: 37935699
Related structures: EMD-36882

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-268651 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Competence factor transporting ATP-binding/permease protein ComA Chains: A, B
Molecule details ›
Chains: A, B
Length: 717 amino acids
Theoretical weight: 80.43 KDa
Source organism: Streptococcus pneumoniae D39
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0H2ZPI8 (Residues: 1-717; Coverage: 100%)
Gene names: SPD_0049, comA
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand ATP 2 x ATP
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.9Å
Relevant EMDB volumes: EMD-36882
Expression system: Escherichia coli

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