8k5d

Electron Microscopy
3.74Å resolution

Cryo-EM structure of GSK256073 bound human hydroxy-carboxylic acid receptor 2 (Local refinement)

Released:

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-235955 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hydroxycarboxylic acid receptor 2 Chain: A
Molecule details ›
Chain: A
Length: 476 amino acids
Theoretical weight: 54.32 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q8TDS4 (Residues: 1-363; Coverage: 100%)
Gene names: GPR109A, HCA2, HCAR2, HM74A, NIACR1
Sequence domains: 7 transmembrane receptor (rhodopsin family)

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.74Å
Relevant EMDB volumes: EMD-36902
Expression system: Spodoptera frugiperda