8k7s

Electron Microscopy
3.51Å resolution

Human Fc epsilon RI in complex with mIgE Fc (TMD disordered)

Released:
Source organisms:
Primary publication:
Architecture of the high-affinity immunoglobulin E receptor.
Sci Signal 17 eadn1303 (2024)
PMID: 39656861
Related structures: EMD-36940

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-281723 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
IgE Fc Chains: E, F
Molecule details ›
Chains: E, F
Length: 356 amino acids
Theoretical weight: 40.37 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
FCER1A Chain: A
Molecule details ›
Chain: A
Length: 280 amino acids
Theoretical weight: 32.58 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.51Å
Relevant EMDB volumes: EMD-36940
Expression system: Homo sapiens