› 8k7t

Electron Microscopy
3.71Å resolution

Mouse Fc epsilon RI in complex with mIgE Fc

Released:
DOI: 10.2210/pdb8k7t/pdb
PDB entry 8k7t coloured by chain, front view.
PDB entry 8k7t coloured by chain, side view.
PDB entry 8k7t coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Zhang Z, Yui M, Ohto U, Shimizu T
Related structures: EMD-36941

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-247161 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (6 distinct):
High affinity immunoglobulin epsilon receptor subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 273 amino acids
Theoretical weight: 31.65 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P20489 (Residues: 1-250; Coverage: 100%)
Gene names: Fce1a, Fcer1a
Sequence domains: Immunoglobulin domain
High affinity immunoglobulin epsilon receptor subunit gamma Chains: G, H
Molecule details ›
Chains: G, H
Length: 104 amino acids
Theoretical weight: 11.89 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P20491 (Residues: 1-86; Coverage: 100%)
Gene names: Fce1g, Fcer1g
Sequence domains:
High affinity immunoglobulin epsilon receptor subunit beta Chain: B
Molecule details ›
Chain: B
Length: 245 amino acids
Theoretical weight: 27.17 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P20490 (Residues: 1-235; Coverage: 100%)
Gene names: Fce1b, Fcer1b, Ms4a1, Ms4a2
Sequence domains: CD20-like family
Immunoglobulin heavy constant epsilon Chains: E, F
Molecule details ›
Chains: E, F
Length: 356 amino acids
Theoretical weight: 40.37 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P06336 (Residues: 91-421; Coverage: 79%)
Gene name: IGHE
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
1 bound ligand:
Ligand NAG 7 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.71Å
Relevant EMDB volumes: EMD-36941
Expression system: Homo sapiens

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