› 8k89

X-ray diffraction
2.1Å resolution

Crystal structure of NFIL3

Released:
DOI: 10.2210/pdb8k89/pdb
PDB entry 8k89 coloured by chain, front view.
PDB entry 8k89 coloured by chain, side view.
PDB entry 8k89 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for specific DNA sequence recognition by the transcription factor NFIL3.
Chen S, Lei M, Liu K, Min J
OpenAccess logo J Biol Chem 105776 (2024)
PMID: 38382670

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-274587 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nuclear factor interleukin-3-regulated protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 98 amino acids
Theoretical weight: 11.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q16649 (Residues: 68-161; Coverage: 20%)
Gene names: E4BP4, IL3BP1, NFIL3
Sequence domains: Basic region leucine zipper

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL02U1
Spacegroup: P212121
Unit cell:
a: 40.116Å b: 65.684Å c: 85.22Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.238 0.235 0.289
Expression system: Escherichia coli BL21(DE3)

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