› 8k8v

Electron Microscopy
2.75Å resolution

CryoEM structure of LonC protease hepatmer, apo state

Released:
DOI: 10.2210/pdb8k8v/pdb
PDB entry 8k8v coloured by chain, front view.
PDB entry 8k8v coloured by chain, side view.
PDB entry 8k8v coloured by chain, top view.
Source organism: Meiothermus taiwanensis
Primary publication:
Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis
Li M, Liu H, Hsieh KY, Zhang S, Gao Y, Gong Q, Zhang K, Chang CI, Li S
Fundam Res (2024)
Related structures: EMD-36965

Function and Biology Details

Reaction catalysed: 
Hydrolysis of proteins in presence of ATP.
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo heptamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-270117 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
endopeptidase La Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 732 amino acids
Theoretical weight: 80.56 KDa
Source organism: Meiothermus taiwanensis
Expression system: Escherichia coli
UniProt:
  • Canonical: C9DRU9 (Residues: 1-719; Coverage: 100%)
Gene names: Mcate_02721, lon_2
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand PO4 7 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.75Å
Relevant EMDB volumes: EMD-36965
Expression system: Escherichia coli

Quick links