› 8kgv

Electron Microscopy
3.2Å resolution

Molecular mechanism of prostaglandin transporter SLCO2A1

Released:
DOI: 10.2210/pdb8kgv/pdb
PDB entry 8kgv coloured by chain, front view.
PDB entry 8kgv coloured by chain, side view.
PDB entry 8kgv coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Li YH, Qu QH, Zhu ZN, Chao YL, Zhou ZX
Related structures: EMD-37233

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-250676 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Solute carrier organic anion transporter family member 2A1 Chain: A
Molecule details ›
Chain: A
Length: 629 amino acids
Theoretical weight: 68.54 KDa
Source organism: Homo sapiens
Expression system: Mammalian expression vector Flag-EGFP-MCS-pcDNA3.1
UniProt:
  • Canonical: Q92959 (Residues: 1-629; Coverage: 98%)
Gene names: OATP2A1, SLC21A2, SLCO2A1
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.2Å
Relevant EMDB volumes: EMD-37233
Expression system: Mammalian expression vector Flag-EGFP-MCS-pcDNA3.1

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