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Cryo-EM structure of the electron bifurcating transhydrogenase StnABC complex from Sporomusa Ovata (state 2)

Source organism: Sporomusa ovata DSM 2662
Biochemical function: metal ion binding
Biological process: not assigned
Cellular component: not assigned

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EC 1.12.1.2: Hydrogen dehydrogenase

Reaction catalysed:
H(2) + NAD(+) = H(+) + NADH
Systematic name:
Hydrogen:NAD(+) oxidoreductase
Alternative Name(s):
  • Bidirectional hydrogenase
  • H(2):NAD(+) oxidoreductase
  • Hydrogenase
  • NAD-linked hydrogenase

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00384
Domain description: Molybdopterin oxidoreductase
Occurring in:
  1. Formate dehydrogenase-O, major subunit
The deposited structure of PDB entry 8oh5 contains 4 copies of Pfam domain PF00384 (Molybdopterin oxidoreductase) in Formate dehydrogenase-O, major subunit. Showing 1 copy in chain C.

PF04879
Domain description: Molybdopterin oxidoreductase Fe4S4 domain
Occurring in:
  1. Formate dehydrogenase-O, major subunit
The deposited structure of PDB entry 8oh5 contains 4 copies of Pfam domain PF04879 (Molybdopterin oxidoreductase Fe4S4 domain) in Formate dehydrogenase-O, major subunit. Showing 1 copy in chain C.

PF12838
Domain description: 4Fe-4S dicluster domain
Occurring in:
  1. Formate dehydrogenase-O, major subunit
The deposited structure of PDB entry 8oh5 contains 4 copies of Pfam domain PF12838 (4Fe-4S dicluster domain) in Formate dehydrogenase-O, major subunit. Showing 1 copy in chain C.

PF07992
Domain description: Pyridine nucleotide-disulphide oxidoreductase
Occurring in:
  1. Formate dehydrogenase-O, major subunit
The deposited structure of PDB entry 8oh5 contains 4 copies of Pfam domain PF07992 (Pyridine nucleotide-disulphide oxidoreductase) in Formate dehydrogenase-O, major subunit. Showing 1 copy in chain C.

PF14691
Domain description: Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
Occurring in:
  1. Formate dehydrogenase-O, major subunit
The deposited structure of PDB entry 8oh5 contains 4 copies of Pfam domain PF14691 (Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster) in Formate dehydrogenase-O, major subunit. Showing 1 copy in chain C.

PF13510
Domain description: 2Fe-2S iron-sulfur cluster binding domain
Occurring in:
  1. Formate dehydrogenase-O, major subunit
The deposited structure of PDB entry 8oh5 contains 4 copies of Pfam domain PF13510 (2Fe-2S iron-sulfur cluster binding domain) in Formate dehydrogenase-O, major subunit. Showing 1 copy in chain C.

PF00037
Domain description: 4Fe-4S binding domain
Occurring in:
  1. 4Fe-4S ferredoxin-type domain-containing protein
The deposited structure of PDB entry 8oh5 contains 4 copies of Pfam domain PF00037 (4Fe-4S binding domain) in 4Fe-4S ferredoxin-type domain-containing protein. Showing 1 copy in chain B.

PF10589
Domain description: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
Occurring in:
  1. 4Fe-4S ferredoxin-type domain-containing protein
The deposited structure of PDB entry 8oh5 contains 4 copies of Pfam domain PF10589 (NADH-ubiquinone oxidoreductase-F iron-sulfur binding region) in 4Fe-4S ferredoxin-type domain-containing protein. Showing 1 copy in chain B.

PF01512
Domain description: Respiratory-chain NADH dehydrogenase 51 Kd subunit
Occurring in:
  1. 4Fe-4S ferredoxin-type domain-containing protein
The deposited structure of PDB entry 8oh5 contains 4 copies of Pfam domain PF01512 (Respiratory-chain NADH dehydrogenase 51 Kd subunit) in 4Fe-4S ferredoxin-type domain-containing protein. Showing 1 copy in chain B.

PF01257
Domain description: Thioredoxin-like [2Fe-2S] ferredoxin
Occurring in:
  1. NAD-dependent formate dehydrogenase gamma subunit
The deposited structure of PDB entry 8oh5 contains 4 copies of Pfam domain PF01257 (Thioredoxin-like [2Fe-2S] ferredoxin) in NAD-dependent formate dehydrogenase gamma subunit. Showing 1 copy in chain A.

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