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39S human mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA

Source organism: Homo sapiens
Biochemical function: structural constituent of ribosome
Biological process: mitochondrial translation
Cellular component: mitochondrion

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EC 3.1.1.29: Aminoacyl-tRNA hydrolase

Reaction catalysed:
N-substituted aminoacyl-tRNA + H(2)O = N-substituted amino acid + tRNA
Systematic name:
Aminoacyl-tRNA aminoacylhydrolase
Alternative Name(s):
  • Aminoacyl-transfer ribonucleate hydrolase
  • N-substituted aminoacyl transfer RNA hydrolase
  • Peptidyl-tRNA hydrolase

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00542
Domain description: Ribosomal protein L7/L12 C-terminal domain
Occurring in:
  1. Large ribosomal subunit protein bL12m
The deposited structure of PDB entry 8oit contains 6 copies of Pfam domain PF00542 (Ribosomal protein L7/L12 C-terminal domain) in Large ribosomal subunit protein bL12m. Showing 1 copy in chain A [auth B1] (this domain is out of the observed residue ranges!).

PF16320
Domain description: Ribosomal protein L7/L12 dimerisation domain
Occurring in:
  1. Large ribosomal subunit protein bL12m
The deposited structure of PDB entry 8oit contains 6 copies of Pfam domain PF16320 (Ribosomal protein L7/L12 dimerisation domain) in Large ribosomal subunit protein bL12m. Showing 1 copy in chain A [auth B1].

PF00297
Domain description: Ribosomal protein L3
Occurring in:
  1. Large ribosomal subunit protein uL3m
The deposited structure of PDB entry 8oit contains 3 copies of Pfam domain PF00297 (Ribosomal protein L3) in Large ribosomal subunit protein uL3m. Showing 3 copies in chain V [auth BM].

PF07147
Domain description: Mitochondrial 28S ribosomal protein S30 (PDCD9)
Occurring in:
  1. Large ribosomal subunit protein mL65
  2. Large ribosomal subunit protein mL37
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF07147 (Mitochondrial 28S ribosomal protein S30 (PDCD9)) in Large ribosomal subunit protein mL65. Showing 1 copy in chain RA [auth Bi].
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF07147 (Mitochondrial 28S ribosomal protein S30 (PDCD9)) in Large ribosomal subunit protein mL37. Showing 1 copy in chain UA [auth Bm].

PF00472
Domain description: RF-1 domain
Occurring in:
  1. Peptide chain release factor 1, mitochondrial
  2. Large ribosomal subunit protein mL62
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00472 (RF-1 domain) in Large ribosomal subunit protein mL62. Showing 1 copy in chain OA [auth Bf].
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00472 (RF-1 domain) in Peptide chain release factor 1, mitochondrial. Showing 1 copy in chain JB [auth Aa].

PF10244
Domain description: Mitochondrial ribosomal subunit
Occurring in:
  1. Large ribosomal subunit protein mL51
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF10244 (Mitochondrial ribosomal subunit) in Large ribosomal subunit protein mL51. Showing 1 copy in chain HB [auth Bz].

PF10501
Domain description: Ribosomal subunit 39S
Occurring in:
  1. Large ribosomal subunit protein mL50
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF10501 (Ribosomal subunit 39S) in Large ribosomal subunit protein mL50. Showing 1 copy in chain GB [auth By].

PF05046
Domain description: Mitochondrial large subunit ribosomal protein (Img2)
Occurring in:
  1. Large ribosomal subunit protein mL49
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF05046 (Mitochondrial large subunit ribosomal protein (Img2)) in Large ribosomal subunit protein mL49. Showing 1 copy in chain FB [auth Bx].

PF00338
Domain description: Ribosomal protein S10p/S20e
Occurring in:
  1. Large ribosomal subunit protein mL48
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00338 (Ribosomal protein S10p/S20e) in Large ribosomal subunit protein mL48. Showing 1 copy in chain EB [auth Bw].

PF11788
Domain description: 39S mitochondrial ribosomal protein L46
Occurring in:
  1. Large ribosomal subunit protein mL46
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF11788 (39S mitochondrial ribosomal protein L46 ) in Large ribosomal subunit protein mL46. Showing 1 copy in chain DB [auth Bv].

PF04280
Domain description: Tim44-like domain
Occurring in:
  1. Large ribosomal subunit protein mL45
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF04280 (Tim44-like domain) in Large ribosomal subunit protein mL45. Showing 1 copy in chain CB [auth Bu].

PF22892
Domain description: MRPL44 dsRNA-binding domain
Occurring in:
  1. Large ribosomal subunit protein mL44
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF22892 (MRPL44 dsRNA-binding domain) in Large ribosomal subunit protein mL44. Showing 1 copy in chain BB [auth Bt].

PF22935
Domain description: Large ribosomal subunit protein mL44, endonuclease domain
Occurring in:
  1. Large ribosomal subunit protein mL44
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF22935 (Large ribosomal subunit protein mL44, endonuclease domain) in Large ribosomal subunit protein mL44. Showing 1 copy in chain BB [auth Bt].

PF05047
Domain description: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
Occurring in:
  1. Large ribosomal subunit protein mL43
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF05047 (Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ) in Large ribosomal subunit protein mL43. Showing 1 copy in chain AB [auth Bs].

PF10210
Domain description: Mitochondrial 28S ribosomal protein S32
Occurring in:
  1. Large ribosomal subunit protein mL42
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF10210 (Mitochondrial 28S ribosomal protein S32) in Large ribosomal subunit protein mL42. Showing 1 copy in chain ZA [auth Br].

PF09809
Domain description: Mitochondrial ribosomal protein L27
Occurring in:
  1. Large ribosomal subunit protein mL41
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF09809 (Mitochondrial ribosomal protein L27) in Large ribosomal subunit protein mL41. Showing 1 copy in chain YA [auth Bq].

PF09812
Domain description: Mitochondrial ribosomal protein L28
Occurring in:
  1. Large ribosomal subunit protein mL40
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF09812 (Mitochondrial ribosomal protein L28) in Large ribosomal subunit protein mL40. Showing 1 copy in chain XA [auth Bp].

PF01161
Domain description: Phosphatidylethanolamine-binding protein
Occurring in:
  1. Large ribosomal subunit protein mL38
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF01161 (Phosphatidylethanolamine-binding protein) in Large ribosomal subunit protein mL38. Showing 1 copy in chain VA [auth Bn].

PF00444
Domain description: Ribosomal protein L36
Occurring in:
  1. Large ribosomal subunit protein bL36m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00444 (Ribosomal protein L36) in Large ribosomal subunit protein bL36m. Showing 1 copy in chain TA [auth Bl].

PF00687
Domain description: Ribosomal protein L1p/L10e family
Occurring in:
  1. Large ribosomal subunit protein uL1m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00687 (Ribosomal protein L1p/L10e family) in Large ribosomal subunit protein uL1m. Showing 1 copy in chain SA [auth Bj].

PF01084
Domain description: Ribosomal protein S18
Occurring in:
  1. Large ribosomal subunit protein mL66
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF01084 (Ribosomal protein S18) in Large ribosomal subunit protein mL66. Showing 1 copy in chain QA [auth Bh].

PF10147
Domain description: Growth arrest and DNA-damage-inducible proteins-interacting protein 1
Occurring in:
  1. Large ribosomal subunit protein mL64
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF10147 (Growth arrest and DNA-damage-inducible proteins-interacting protein 1) in Large ribosomal subunit protein mL64. Showing 1 copy in chain PA [auth Bg].

PF14978
Domain description: Mitochondrial ribosome protein 63
Occurring in:
  1. Large ribosomal subunit protein mL63
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF14978 (Mitochondrial ribosome protein 63) in Large ribosomal subunit protein mL63. Showing 1 copy in chain NA [auth Be].

PF09776
Domain description: Mitochondrial ribosomal protein L55
Occurring in:
  1. Large ribosomal subunit protein mL55
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF09776 (Mitochondrial ribosomal protein L55) in Large ribosomal subunit protein mL55. Showing 1 copy in chain MA [auth Bd].

PF08561
Domain description: Mitochondrial ribosomal protein L37
Occurring in:
  1. Large ribosomal subunit protein mL54
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF08561 (Mitochondrial ribosomal protein L37) in Large ribosomal subunit protein mL54. Showing 1 copy in chain LA [auth Bc].

PF10780
Domain description: 39S ribosomal protein L53/MRP-L53
Occurring in:
  1. Large ribosomal subunit protein mL53
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF10780 (39S ribosomal protein L53/MRP-L53) in Large ribosomal subunit protein mL53. Showing 1 copy in chain KA [auth Bb].

PF18699
Domain description: Mitoribosomal protein mL52
Occurring in:
  1. Large ribosomal subunit protein mL52
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF18699 (Mitoribosomal protein mL52 ) in Large ribosomal subunit protein mL52. Showing 1 copy in chain JA [auth Ba].

PF00829
Domain description: Ribosomal prokaryotic L21 protein
Occurring in:
  1. Large ribosomal subunit protein bL21m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00829 (Ribosomal prokaryotic L21 protein) in Large ribosomal subunit protein bL21m. Showing 1 copy in chain IA [auth BZ].

PF00453
Domain description: Ribosomal protein L20
Occurring in:
  1. Large ribosomal subunit protein bL20m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00453 (Ribosomal protein L20) in Large ribosomal subunit protein bL20m. Showing 1 copy in chain HA [auth BY].

PF01245
Domain description: Ribosomal protein L19
Occurring in:
  1. Large ribosomal subunit protein bL19m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF01245 (Ribosomal protein L19) in Large ribosomal subunit protein bL19m. Showing 1 copy in chain GA [auth BX].

PF00861
Domain description: Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
Occurring in:
  1. Large ribosomal subunit protein uL18m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00861 (Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast) in Large ribosomal subunit protein uL18m. Showing 1 copy in chain FA [auth BW].

PF01196
Domain description: Ribosomal protein L17
Occurring in:
  1. Large ribosomal subunit protein bL17m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF01196 (Ribosomal protein L17) in Large ribosomal subunit protein bL17m. Showing 1 copy in chain EA [auth BV].

PF00252
Domain description: Ribosomal protein L16p/L10e
Occurring in:
  1. Large ribosomal subunit protein uL16m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00252 (Ribosomal protein L16p/L10e) in Large ribosomal subunit protein uL16m. Showing 1 copy in chain DA [auth BU].

PF00828
Domain description: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
Occurring in:
  1. Large ribosomal subunit protein uL15m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00828 (Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A) in Large ribosomal subunit protein uL15m. Showing 1 copy in chain CA [auth BT].

PF00238
Domain description: Ribosomal protein L14p/L23e
Occurring in:
  1. Large ribosomal subunit protein uL14m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00238 (Ribosomal protein L14p/L23e) in Large ribosomal subunit protein uL14m. Showing 1 copy in chain BA [auth BS].

PF00572
Domain description: Ribosomal protein L13
Occurring in:
  1. Large ribosomal subunit protein uL13m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00572 (Ribosomal protein L13) in Large ribosomal subunit protein uL13m. Showing 1 copy in chain AA [auth BR].

PF00298
Domain description: Ribosomal protein L11, RNA binding domain
Occurring in:
  1. Large ribosomal subunit protein uL11m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00298 (Ribosomal protein L11, RNA binding domain) in Large ribosomal subunit protein uL11m. Showing 1 copy in chain Z [auth BQ].

PF03946
Domain description: Ribosomal protein L11, N-terminal domain
Occurring in:
  1. Large ribosomal subunit protein uL11m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF03946 (Ribosomal protein L11, N-terminal domain) in Large ribosomal subunit protein uL11m. Showing 1 copy in chain Z [auth BQ].

PF00466
Domain description: Ribosomal protein L10
Occurring in:
  1. Large ribosomal subunit protein uL10m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00466 (Ribosomal protein L10) in Large ribosomal subunit protein uL10m. Showing 1 copy in chain Y [auth BP].

PF22078
Domain description: Large ribosomal subunit protein bL9m C-terminal domain
Occurring in:
  1. Large ribosomal subunit protein bL9m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF22078 (Large ribosomal subunit protein bL9m C-terminal domain) in Large ribosomal subunit protein bL9m. Showing 1 copy in chain X [auth BO].

PF01281
Domain description: Ribosomal protein L9, N-terminal domain
Occurring in:
  1. Large ribosomal subunit protein bL9m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF01281 (Ribosomal protein L9, N-terminal domain) in Large ribosomal subunit protein bL9m. Showing 1 copy in chain X [auth BO].

PF00573
Domain description: Ribosomal protein L4/L1 family
Occurring in:
  1. Large ribosomal subunit protein uL4m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00573 (Ribosomal protein L4/L1 family) in Large ribosomal subunit protein uL4m. Showing 1 copy in chain W [auth BN].

PF03947
Domain description: Ribosomal Proteins L2, C-terminal domain
Occurring in:
  1. Large ribosomal subunit protein uL2m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF03947 (Ribosomal Proteins L2, C-terminal domain) in Large ribosomal subunit protein uL2m. Showing 1 copy in chain U [auth BL].

PF00181
Domain description: Ribosomal Proteins L2, RNA binding domain
Occurring in:
  1. Large ribosomal subunit protein uL2m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00181 (Ribosomal Proteins L2, RNA binding domain) in Large ribosomal subunit protein uL2m. Showing 1 copy in chain U [auth BL].

PF01632
Domain description: Ribosomal protein L35
Occurring in:
  1. Large ribosomal subunit protein bL35m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF01632 (Ribosomal protein L35) in Large ribosomal subunit protein bL35m. Showing 1 copy in chain T [auth BK].

PF00468
Domain description: Ribosomal protein L34
Occurring in:
  1. Large ribosomal subunit protein bL34m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00468 (Ribosomal protein L34) in Large ribosomal subunit protein bL34m. Showing 1 copy in chain S [auth BJ].

PF00471
Domain description: Ribosomal protein L33
Occurring in:
  1. Large ribosomal subunit protein bL33m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00471 (Ribosomal protein L33) in Large ribosomal subunit protein bL33m. Showing 1 copy in chain R [auth BI].

PF01783
Domain description: Ribosomal L32p protein family
Occurring in:
  1. Large ribosomal subunit protein bL32m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF01783 (Ribosomal L32p protein family) in Large ribosomal subunit protein bL32m. Showing 1 copy in chain Q [auth BH].

PF00327
Domain description: Ribosomal protein L30p/L7e
Occurring in:
  1. Large ribosomal subunit protein uL30m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00327 (Ribosomal protein L30p/L7e) in Large ribosomal subunit protein uL30m. Showing 1 copy in chain P [auth BG].

PF06984
Domain description: Mitochondrial 39-S ribosomal protein L47 (MRP-L47)
Occurring in:
  1. Large ribosomal subunit protein uL29m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF06984 (Mitochondrial 39-S ribosomal protein L47 (MRP-L47)) in Large ribosomal subunit protein uL29m. Showing 1 copy in chain O [auth BF].

PF00830
Domain description: Ribosomal L28 family
Occurring in:
  1. Large ribosomal subunit protein bL28m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00830 (Ribosomal L28 family) in Large ribosomal subunit protein bL28m. Showing 1 copy in chain N [auth BE].

PF01016
Domain description: Ribosomal L27 protein
Occurring in:
  1. Large ribosomal subunit protein bL27m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF01016 (Ribosomal L27 protein) in Large ribosomal subunit protein bL27m. Showing 1 copy in chain M [auth BD].

PF17136
Domain description: Ribosomal proteins 50S L24/mitochondrial 39S L24
Occurring in:
  1. Large ribosomal subunit protein uL24m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF17136 (Ribosomal proteins 50S L24/mitochondrial 39S L24) in Large ribosomal subunit protein uL24m. Showing 1 copy in chain L [auth BC].

PF00467
Domain description: KOW motif
Occurring in:
  1. Large ribosomal subunit protein uL24m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00467 (KOW motif) in Large ribosomal subunit protein uL24m. Showing 1 copy in chain L [auth BC].

PF00276
Domain description: Ribosomal protein L23
Occurring in:
  1. Large ribosomal subunit protein uL23m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00276 (Ribosomal protein L23) in Large ribosomal subunit protein uL23m. Showing 1 copy in chain K [auth BB].

PF00237
Domain description: Ribosomal protein L22p/L17e
Occurring in:
  1. Large ribosomal subunit protein uL22m
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF00237 (Ribosomal protein L22p/L17e) in Large ribosomal subunit protein uL22m. Showing 1 copy in chain J [auth BA].

PF03462
Domain description: PCRF domain
Occurring in:
  1. Peptide chain release factor 1, mitochondrial
The deposited structure of PDB entry 8oit contains 1 copy of Pfam domain PF03462 (PCRF domain) in Peptide chain release factor 1, mitochondrial. Showing 1 copy in chain JB [auth Aa].

Rfam RNA family (Rfam)
RF02541
Domain description: Bacterial large subunit ribosomal RNA
Occurring in:
  1. 16S ribosomal RNA
The deposited structure of PDB entry 8oit contains 1 copy of Rfam domain RF02541 (Bacterial large subunit ribosomal RNA) in 16S ribosomal RNA. Showing 1 copy in chain H [auth B8].

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