› 8oj4

Electron Microscopy
4.35Å resolution

Structure of the MlaCD complex (1:6 stoichiometry)

Released:
DOI: 10.2210/pdb8oj4/pdb
PDB entry 8oj4 coloured by chain, front view.
PDB entry 8oj4 coloured by chain, side view.
PDB entry 8oj4 coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Structure of the MlaC-MlaD complex reveals molecular basis of periplasmic phospholipid transport.
Wotherspoon P, Johnston H, Hardy DJ, Holyfield R, Bui S, Ratkevičiūtė G, Sridhar P, Colburn J, Wilson CB, Colyer A, Cooper BF, Bryant JA, Hughes GW, Stansfeld PJ, Bergeron JRC, Knowles TJ
Nat Commun 15 6394 (2024)
PMID: 39080293
Related structures: EMD-16904

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero heptamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-272640 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Intermembrane phospholipid transport system binding protein MlaC Chain: H
Molecule details ›
Chain: H
Length: 211 amino acids
Theoretical weight: 23.99 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0ADV7 (Residues: 1-211; Coverage: 100%)
Gene names: JW3159, b3192, mlaC, yrbC
Sequence domains: MlaC protein
Intermembrane phospholipid transport system binding protein MlaD Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 183 amino acids
Theoretical weight: 19.59 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P64604 (Residues: 1-183; Coverage: 100%)
Gene names: JW3160, b3193, mlaD, yrbD
Sequence domains: MlaD protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.35Å
Relevant EMDB volumes: EMD-16904
Expression system: Escherichia coli

Quick links