› 8ojr

Solution NMR

Solution NMR Structure of Alpha-Synuclein 1-25 Peptide in 50% TFE.

Released:
DOI: 10.2210/pdb8ojr/pdb
PDB entry 8ojr coloured by chain, ensemble of 20 models, front view.
PDB entry 8ojr coloured by chain, ensemble of 20 models, side view.
PDB entry 8ojr coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
An N-terminal alpha-Synuclein fragment binds lipid vesicles to modulate lipid induced aggregation
Meade RM, Allen SG, Williams C, Tang TMS, Crump MP, Mason JM
Cell Rep Phys Sci (2023)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153495 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-synuclein Chain: A
Molecule details ›
Chain: A
Length: 27 amino acids
Theoretical weight: 2.65 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P37840 (Residues: 1-25; Coverage: 18%)
Gene names: NACP, PARK1, SNCA

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 75%
Refinement method: molecular dynamics
Expression system: Not provided

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