› 8on7

Electron Microscopy
2.5Å resolution

FMRFa-bound Malacoceros FaNaC1 in lipid nanodiscs

Released:
DOI: 10.2210/pdb8on7/pdb
PDB entry 8on7 coloured by chain, front view.
PDB entry 8on7 coloured by chain, side view.
PDB entry 8on7 coloured by chain, top view.
Source organism: Malacoceros fuliginosus
Primary publication:
Structural basis for excitatory neuropeptide signaling.
Kalienkova V, Dandamudi M, Paulino C, Lynagh T
OpenAccess logo Nat Struct Mol Biol (2024)
PMID: 38337033
Related structures: EMD-16981

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-239944 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
FMRFamide-gated sodium channel 1 (FaNaC1) Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 600 amino acids
Theoretical weight: 68.61 KDa
Source organism: Malacoceros fuliginosus
Expression system: Homo sapiens
FMRFamide, neuropeptide Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 5 amino acids
Theoretical weight: 599 Da
Source organism: Malacoceros fuliginosus
Expression system: Not provided

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 9 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.5Å
Relevant EMDB volumes: EMD-16981
Expression systems:
  • Homo sapiens
  • Not provided

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