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8onv Overview
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>8onv</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTPase KRas, N-terminally processed</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GUANOSINE-5'-DIPHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8onv_assembly_1_chemically_distinct_molecules_front_image-800x800.png "Monomeric assembly 1 of PDB entry 8onv coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>8onv</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTPase KRas, N-terminally processed</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GUANOSINE-5'-DIPHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8onv_assembly_1_chemically_distinct_molecules_side_image-800x800.png "Monomeric assembly 1 of PDB entry 8onv coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>8onv</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTPase KRas, N-terminally processed</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GUANOSINE-5'-DIPHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8onv_assembly_1_chemically_distinct_molecules_top_image-800x800.png "Monomeric assembly 1 of PDB entry 8onv coloured by chemically distinct molecules, top view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>8onv</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTPase KRas, N-terminally processed</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GUANOSINE-5'-DIPHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8onv_assembly_1_chain_front_image-800x800.png "Monomeric assembly 1 of PDB entry 8onv coloured by chain, front view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>8onv</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTPase KRas, N-terminally processed</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GUANOSINE-5'-DIPHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8onv_assembly_1_chain_side_image-800x800.png "Monomeric assembly 1 of PDB entry 8onv coloured by chain, side view.")
![<div class='caption-body'>Monomeric assembly 1 of PDB entry <span class='highlight'>8onv</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTPase KRas, N-terminally processed</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GUANOSINE-5'-DIPHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8onv_assembly_1_chain_top_image-800x800.png "Monomeric assembly 1 of PDB entry 8onv coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8onv</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTPase KRas, N-terminally processed</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GUANOSINE-5'-DIPHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8onv_deposited_chain_front_image-800x800.png "PDB entry 8onv coloured by chain, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8onv</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTPase KRas, N-terminally processed</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GUANOSINE-5'-DIPHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8onv_deposited_chain_side_image-800x800.png "PDB entry 8onv coloured by chain, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8onv</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTPase KRas, N-terminally processed</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GUANOSINE-5'-DIPHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8onv_deposited_chain_top_image-800x800.png "PDB entry 8onv coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8onv</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTPase KRas, N-terminally processed</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GUANOSINE-5'-DIPHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8onv_deposited_chemically_distinct_molecules_front_image-800x800.png "PDB entry 8onv coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8onv</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTPase KRas, N-terminally processed</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GUANOSINE-5'-DIPHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8onv_deposited_chemically_distinct_molecules_side_image-800x800.png "PDB entry 8onv coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8onv</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>GTPase KRas, N-terminally processed</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>GUANOSINE-5'-DIPHOSPHATE</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>MAGNESIUM ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1,2-ETHANEDIOL</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>(7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8onv_deposited_chemically_distinct_molecules_top_image-800x800.png "PDB entry 8onv coloured by chemically distinct molecules, top view.")