› 8oqg

X-ray diffraction
1.6Å resolution

Cross-linked crystal of dirhodium tetraacetate/ribonuclease A adduct in the P3221 space group (high temperature data collection)

Released:
DOI: 10.2210/pdb8oqg/pdb
PDB entry 8oqg coloured by chain, front view.
PDB entry 8oqg coloured by chain, side view.
PDB entry 8oqg coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Cross-Linked Crystals of Dirhodium Tetraacetate/RNase A Adduct Can Be Used as Heterogeneous Catalysts.
Loreto D, Maity B, Morita T, Nakamura H, Merlino A, Ueno T
OpenAccess logo Inorg Chem 62 7515-7524 (2023)
PMID: 37144589

Function and Biology Details

Reaction catalysed: 
(1a) an (RNA) containing cytidine = an (RNA)-3'-cytidine-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158390 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribonuclease pancreatic Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 13.71 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P61823 (Residues: 27-150; Coverage: 100%)
Gene names: RNASE1, RNS1
Sequence domains: Pancreatic ribonuclease

Ligands and Environments

4 bound ligands:
Ligand VVU 1 x VVU
Ligand VW5 1 x VW5
Ligand FMT 1 x FMT
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU PhotonJet-R
Spacegroup: P3221
Unit cell:
a: 67.278Å b: 67.278Å c: 65.899Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.183 0.182 0.202

Quick links

Citations

1 mention without citation

Cross-Linked Crystals of Dirhodium Tetraacetate/RNase A Adduct Can Be Used as Heterogeneous Catalysts.
Loreto et al. (2023)