› 8oqh

X-ray diffraction
1.76Å resolution

Structure of the cytosolic domain of lysosome-associated TMEM55B

Released:
DOI: 10.2210/pdb8oqh/pdb
PDB entry 8oqh coloured by chain, front view.
PDB entry 8oqh coloured by chain, side view.
PDB entry 8oqh coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Waschbusch D, Khan AR

Function and Biology Details

Reaction catalysed: 
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-236127 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase Chains: A, B
Molecule details ›
Chains: A, B
Length: 91 amino acids
Theoretical weight: 9.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q86T03 (Residues: 73-159; Coverage: 31%)
Gene names: C14orf9, PIP4P1, TMEM55B
Sequence domains: Transmembrane protein 55A

Ligands and Environments

1 bound ligand:
Ligand ZN 4 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P21
Unit cell:
a: 29.412Å b: 84.445Å c: 32.177Å
α: 90° β: 98.32° γ: 90°
R-values:
R R work R free
0.196 0.194 0.224
Expression system: Escherichia coli

Quick links