› 8os2

X-ray diffraction
1.64Å resolution

Structure of the human LYVE-1 (lymphatic vessel endothelial receptor-1) hyaluronan binding domain in an unliganded state

Released:
DOI: 10.2210/pdb8os2/pdb
PDB entry 8os2 coloured by chain, front view.
PDB entry 8os2 coloured by chain, side view.
PDB entry 8os2 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Ni T, Bannerji S, Jackson DJ, Gilbert RJC

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-247791 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lymphatic vessel endothelial hyaluronic acid receptor 1 Chain: A
Molecule details ›
Chain: A
Length: 146 amino acids
Theoretical weight: 16.1 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: Q9Y5Y7 (Residues: 1-144; Coverage: 41%)
Gene names: CRSBP1, HAR, LYVE1, UNQ230/PRO263, XLKD1
Sequence domains: Extracellular link domain

Ligands and Environments

2 bound ligands:
Ligand NAG 2 x NAG
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P41212
Unit cell:
a: 70.81Å b: 70.81Å c: 75.77Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.183 0.223
Expression system: Cricetulus griseus

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