Function and Biology

Ternary structure of intramolecular bivalent glue degrader IBG1 bound to BRD4 and DCAF16:DDB1deltaBPB

Source organism: Homo sapiens
Biochemical function: protein binding
Biological process: protein ubiquitination
Cellular component: nucleus

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00439
Domain description: Bromodomain
Occurring in:
  1. Bromodomain-containing protein 4
The deposited structure of PDB entry 8ov6 contains 2 copies of Pfam domain PF00439 (Bromodomain) in Bromodomain-containing protein 4. Showing 2 copies in chain C.

PF15349
Domain description: DDB1- and CUL4-associated factor 16
Occurring in:
  1. DDB1- and CUL4-associated factor 16
The deposited structure of PDB entry 8ov6 contains 1 copy of Pfam domain PF15349 (DDB1- and CUL4-associated factor 16) in DDB1- and CUL4-associated factor 16. Showing 1 copy in chain B.

PF03178
Domain description: CPSF A subunit region
Occurring in:
  1. DNA damage-binding protein 1
The deposited structure of PDB entry 8ov6 contains 1 copy of Pfam domain PF03178 (CPSF A subunit region) in DNA damage-binding protein 1. Showing 1 copy in chain A.

PF10433
Domain description: Mono-functional DNA-alkylating methyl methanesulfonate N-term
Occurring in:
  1. DNA damage-binding protein 1
The deposited structure of PDB entry 8ov6 contains 1 copy of Pfam domain PF10433 (Mono-functional DNA-alkylating methyl methanesulfonate N-term) in DNA damage-binding protein 1. Showing 1 copy in chain A.