8ovb

Electron Microscopy
3.4Å resolution

Human Complement C3b in complex with Trypanosoma brucei ISG65.

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-239845 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Complement C3 beta chain Chain: A
Molecule details ›
Chain: A
Length: 642 amino acids
Theoretical weight: 71.15 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01024 (Residues: 23-664; Coverage: 39%)
Gene names: C3, CPAMD1
Sequence domains:
Complement C3b alpha' chain Chain: B
Molecule details ›
Chain: B
Length: 915 amino acids
Theoretical weight: 104.07 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01024 (Residues: 749-1663; Coverage: 56%)
Gene names: C3, CPAMD1
Sequence domains:
65 kDa invariant surface glycoprotein Chain: C
Molecule details ›
Chain: C
Length: 289 amino acids
Theoretical weight: 32.6 KDa
Source organism: Trypanosoma brucei brucei
Expression system: Homo sapiens
UniProt:
  • Canonical: A0A8J9S0Z8 (Residues: 25-313; Coverage: 69%)
Gene name: ISG65 G
Sequence domains: Invariant surface glycoprotein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.4Å
Relevant EMDB volumes: EMD-17209
Expression system: Homo sapiens