› 8owv

X-ray diffraction
1.73Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-276097 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike protein S1 Chain: EEE
Molecule details ›
Chain: EEE
Length: 209 amino acids
Theoretical weight: 23.64 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 331-532; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
F2 Chain: BBB
Molecule details ›
Chain: BBB
Length: 132 amino acids
Theoretical weight: 14.96 KDa
Source organism: Lama glama
Expression system: Escherichia coli
H6 Chain: FFF
Molecule details ›
Chain: FFF
Length: 133 amino acids
Theoretical weight: 14.59 KDa
Source organism: Lama glama
Expression system: Escherichia coli

Ligands and Environments

2 bound ligands:
Ligand NAG 1 x NAG
Ligand GOL 3 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 57.775Å b: 59.438Å c: 145.624Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.197 0.223
Expression systems:
  • Homo sapiens
  • Escherichia coli

Quick links

Citations

1 citations in other articles

Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.
Cornish et al. (2024)