› 8oyr

X-ray diffraction
2.21Å resolution

DNA Major Groove Binding by lambda-[Ru(phen)2(phi)]2+

Released:
DOI: 10.2210/pdb8oyr/pdb
PDB entry 8oyr coloured by chain, front view.
PDB entry 8oyr coloured by chain, side view.
PDB entry 8oyr coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Probing a Major DNA Weakness: Resolving the Groove and Sequence Selectivity of the Diimine Complex Λ-[Ru(phen)2 phi]2.
Prieto Otoya TD, McQuaid KT, Hennessy J, Menounou G, Gibney A, Paterson NG, Cardin DJ, Kellett A, Cardin CJ
Angew Chem Int Ed Engl e202318863 (2024)
PMID: 38271265

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-241191 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*CP*GP*GP*TP*AP*CP*CP*GP*G)-3') Chain: A
Molecule details ›
Chain: A
Length: 10 nucleotides
Theoretical weight: 3.05 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand V7F 3 x V7F
Ligand SR 2 x SR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P422
Unit cell:
a: 56.99Å b: 56.99Å c: 30.892Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.233 0.23 0.263
Expression system: Not provided

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