› 8p7a

X-ray diffraction
2.56Å resolution

Crystal structure of the ORD domain of human ORP8

Released:
DOI: 10.2210/pdb8p7a/pdb
PDB entry 8p7a coloured by chain, front view.
PDB entry 8p7a coloured by chain, side view.
PDB entry 8p7a coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal Structure of the ORP8 Lipid Transport ORD Domain: Model of Lipid Transport.
Eisenreichova A, Klima M, Anila MM, Koukalova A, Humpolickova J, Różycki B, Boura E
OpenAccess logo Cells 12 (2023)
PMID: 37566053

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189858 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Oxysterol-binding protein-related protein 8 Chains: A, B
Molecule details ›
Chains: A, B
Length: 381 amino acids
Theoretical weight: 44.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9BZF1 (Residues: 411-791; Coverage: 43%)
Gene names: KIAA1451, ORP8, OSBP10, OSBPL8
Sequence domains: Oxysterol-binding protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P21212
Unit cell:
a: 105.61Å b: 190.24Å c: 58.72Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.219 0.251
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 mention without citation

Crystal Structure of the ORP8 Lipid Transport ORD Domain: Model of Lipid Transport.
Eisenreichova et al. (2023)