› 8pd9

Electron Microscopy
3.6Å resolution

cAMP-bound SpSLC9C1 in lipid nanodiscs, protomer state 1

Released:
DOI: 10.2210/pdb8pd9/pdb
PDB entry 8pd9 coloured by chain, front view.
PDB entry 8pd9 coloured by chain, side view.
PDB entry 8pd9 coloured by chain, top view.
Source organism: Strongylocentrotus purpuratus
Primary publication:
Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Kalienkova V, Peter MF, Rheinberger J, Paulino C
OpenAccess logo Nature 623 202-209 (2023)
PMID: 37880361
Related structures: EMD-17607

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-234926 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sperm-specific sodium:proton exchanger Chain: A
Molecule details ›
Chain: A
Length: 1333 amino acids
Theoretical weight: 147.62 KDa
Source organism: Strongylocentrotus purpuratus
Expression system: Homo sapiens
UniProt:
  • Canonical: A3RL54 (Residues: 2-1325; Coverage: 100%)
Gene name: SLC9C1
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand CMP 1 x CMP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.6Å
Relevant EMDB volumes: EMD-17607
Expression system: Homo sapiens

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