› 8pfl

X-ray diffraction
1.8Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171958 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Chain: A
Molecule details ›
Chain: A
Length: 431 amino acids
Theoretical weight: 48.63 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q14191 (Residues: 517-945; Coverage: 30%)
Gene names: RECQ3, RECQL2, WRN
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand ZN 1 x ZN
Ligand YH8 1 x YH8
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P212121
Unit cell:
a: 40.231Å b: 87.484Å c: 133.878Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.197 0.226
Expression system: Spodoptera frugiperda

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