› 8phn

X-ray diffraction
1.9Å resolution

Receiver domain from hybrid Histidine Kinase 3 from Chaetomium thermophilum

Released:
DOI: 10.2210/pdb8phn/pdb
PDB entry 8phn coloured by chain, front view.
PDB entry 8phn coloured by chain, side view.
PDB entry 8phn coloured by chain, top view.
Source organism: Chaetomium thermophilum
Primary publication:
Structural and functional insights underlying recognition of histidine phosphotransfer protein in fungal phosphorelay systems.
Paredes-Martínez F, Eixerés L, Zamora-Caballero S, Casino P
OpenAccess logo Commun Biol 7 814 (2024)
PMID: 38965424

Function and Biology Details

Reaction catalysed: 
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-515037 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
histidine kinase Chain: A
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 15.41 KDa
Source organism: Chaetomium thermophilum
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: G0SBK1 (Residues: 1085-1220; Coverage: 10%)
Gene name: CTHT_0053860
Sequence domains: Response regulator receiver domain

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: F432
Unit cell:
a: 154.268Å b: 154.268Å c: 154.268Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.211 0.222
Expression system: Escherichia coli K-12

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