› 8pi0

Solution NMR

NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with 5-(1H-indol-2-l)piperazin-2-one

Released:
DOI: 10.2210/pdb8pi0/pdb
PDB entry 8pi0 coloured by chain, ensemble of 4 models, front view.
PDB entry 8pi0 coloured by chain, ensemble of 4 models, side view.
PDB entry 8pi0 coloured by chain, ensemble of 4 models, top view.
Source organism: Homo sapiens
Entry authors: Buetikofer M, Orts J

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-246967 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b Chain: A
Molecule details ›
Chain: A
Length: 168 amino acids
Theoretical weight: 19.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments

1 bound ligand:
Ligand YVW 1 x YVW
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 1%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

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