› 8pks

X-ray diffraction
2.6Å resolution

Low resolution crystal structure of Keap1-456, a repeat fragment from the human Keap1 beta-propeller

Released:
DOI: 10.2210/pdb8pks/pdb
PDB entry 8pks coloured by chain, front view.
PDB entry 8pks coloured by chain, side view.
PDB entry 8pks coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Wouters SML

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171937 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kelch-like ECH-associated protein 1 Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N
Length: 143 amino acids
Theoretical weight: 15.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q14145 (Residues: 471-609; Coverage: 22%)
Gene names: INRF2, KEAP1, KIAA0132, KLHL19
Sequence domains: Kelch motif

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P212121
Unit cell:
a: 46.846Å b: 220.962Å c: 248.75Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.214 0.259
Expression system: Escherichia coli BL21

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