› 8pmv

X-ray diffraction
2.1Å resolution

transcription factor BARHL2 bound to TAAGC DNA sequence

Released:
DOI: 10.2210/pdb8pmv/pdb
PDB entry 8pmv coloured by chain, front view.
PDB entry 8pmv coloured by chain, side view.
PDB entry 8pmv coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Morgunova E, Popov A, Yin Y, Taipale J

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-270659 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
BarH-like 2 homeobox protein Chains: A, D, G, J
Molecule details ›
Chains: A, D, G, J
Length: 62 amino acids
Theoretical weight: 7.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NY43 (Residues: 231-292; Coverage: 16%)
Gene name: BARHL2
Sequence domains: Homeodomain
DNA Chains: B, E, H, K
Molecule details ›
Chains: B, E, H, K
Length: 12 nucleotides
Theoretical weight: 3.68 KDa
Source organism: Homo sapiens
Expression system: Not provided
DNA Chains: C, F, I, L
Molecule details ›
Chains: C, F, I, L
Length: 12 nucleotides
Theoretical weight: 3.65 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21
Unit cell:
a: 39.08Å b: 133.773Å c: 64.99Å
α: 90° β: 92.74° γ: 90°
R-values:
R R work R free
0.253 0.251 0.278
Expression systems:
  • Escherichia coli
  • Not provided

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