› 8poe

Electron Microscopy
4.2Å resolution

Structure of tissue-specific lipid scramblase ATG9B homotrimer, refined with C3 symmetry applied

Released:
DOI: 10.2210/pdb8poe/pdb
PDB entry 8poe coloured by chain, front view.
PDB entry 8poe coloured by chain, side view.
PDB entry 8poe coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
ATG9B is a tissue-specific homotrimeric lipid scramblase that can compensate for ATG9A.
Chiduza GN, Garza-Garcia A, Almacellas E, De Tito S, Pye VE, van Vliet AR, Cherepanov P, Tooze SA
Autophagy 1-20 (2023)
PMID: 37938170
Related structures: EMD-17789

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-235934 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Autophagy-related protein 9B Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 960 amino acids
Theoretical weight: 105.67 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q674R7 (Residues: 2-924; Coverage: 100%)
Gene names: APG9L2, ATG9B, NOS3AS
Sequence domains: Autophagy protein ATG9

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.2Å
Relevant EMDB volumes: EMD-17789
Expression system: Homo sapiens

Quick links