› 8ptq

X-ray diffraction
1.55Å resolution

Function and Biology Details

Reaction catalysed: 
Hydrolyzes glycerol monoesters of long-chain fatty acids
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189244 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Monoglyceride lipase Chain: A
Molecule details ›
Chain: A
Length: 323 amino acids
Theoretical weight: 35.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99685 (Residues: 1-303; Coverage: 100%)
Gene name: MGLL
Sequence domains: Serine aminopeptidase, S33

Ligands and Environments

2 bound ligands:
Ligand EJI 1 x EJI
Ligand EDO 2 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: C2221
Unit cell:
a: 90.958Å b: 126.448Å c: 60.271Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.195 0.226
Expression system: Escherichia coli

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