› 8qck

X-ray diffraction
4.7Å resolution

Crystal structure of mycothiol disulfide reductase Mtr from Mycobacterium smegmatis

Released:
DOI: 10.2210/pdb8qck/pdb
PDB entry 8qck coloured by chain, front view.
PDB entry 8qck coloured by chain, side view.
PDB entry 8qck coloured by chain, top view.
Source organism: Mycolicibacterium smegmatis MC2 155
Primary publication:
The crystal structure of mycothiol disulfide reductase (Mtr) provides mechanistic insight into the specific low-molecular-weight thiol reductase activity of Actinobacteria.
Gutiérrez-Fernández J, Hersleth HP, Hammerstad M
OpenAccess logo Acta Crystallogr D Struct Biol 80 181-193 (2024)
PMID: 38372589

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-245653 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pyridine nucleotide-disulphide oxidoreductase family protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 461 amino acids
Theoretical weight: 50 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
Expression system: Escherichia coli
UniProt:
  • Canonical: A0QVL0 (Residues: 1-461; Coverage: 100%)
Gene name: MSMEG_2611
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: C2221
Unit cell:
a: 51.959Å b: 209.563Å c: 241.871Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.297 0.292 0.338
Expression system: Escherichia coli

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