› 8qcy

Electron Microscopy
2.9Å resolution

Cryo-EM structure of the outward-facing FLVCR2

Released:
DOI: 10.2210/pdb8qcy/pdb
PDB entry 8qcy coloured by chain, front view.
PDB entry 8qcy coloured by chain, side view.
PDB entry 8qcy coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Molecular mechanism of choline and ethanolamine transport in humans.
Ri K, Weng TH, Claveras Cabezudo A, Jösting W, Zhang Y, Bazzone A, Leong NCP, Welsch S, Doty RT, Gursu G, Lim TJY, Schmidt SL, Abkowitz JL, Hummer G, Wu D, Nguyen LN, Safarian S
Nature (2024)
PMID: 38778100
Related structures: EMD-18337

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-243218 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heme transporter FLVCR2 Chain: A
Molecule details ›
Chain: A
Length: 534 amino acids
Theoretical weight: 58.28 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9UPI3 (Residues: 1-526; Coverage: 100%)
Gene names: C14orf58, FLVCR2
Sequence domains: Major Facilitator Superfamily

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.9Å
Relevant EMDB volumes: EMD-18337
Expression system: Homo sapiens

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