› 8qe5

Electron Microscopy
2.6Å resolution

Apo Hantaan virus polymerase in monomeric state

Released:
DOI: 10.2210/pdb8qe5/pdb
PDB entry 8qe5 coloured by chain, front view.
PDB entry 8qe5 coloured by chain, side view.
PDB entry 8qe5 coloured by chain, top view.
Source organism: Hantaan virus 76-118
Primary publication:
Structural characterization of the oligomerization of full-length Hantaan virus polymerase into symmetric dimers and hexamers.
Durieux Trouilleton Q, Housset D, Tarillon P, Arragain B, Malet H
Nat Commun 15 2256 (2024)
PMID: 38480734
Related structures: EMD-18343

Function and Biology Details

Reaction catalysed: 
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149965 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA-directed RNA polymerase L Chain: A
Molecule details ›
Chain: A
Length: 2173 amino acids
Theoretical weight: 249.48 KDa
Source organism: Hantaan virus 76-118
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P23456 (Residues: 1-2151; Coverage: 100%)
Gene name: L
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.6Å
Relevant EMDB volumes: EMD-18343
Expression system: Trichoplusia ni

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