› 8qf5

X-ray diffraction
1.5Å resolution

Complex between N-lobe of Arc and nanobody E5

Released:
DOI: 10.2210/pdb8qf5/pdb
PDB entry 8qf5 coloured by chain, front view.
PDB entry 8qf5 coloured by chain, side view.
PDB entry 8qf5 coloured by chain, top view.
Source organisms:
Entry authors: Godoy Munoz JM, Kursula P

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-274999 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nanobody E5 Chains: A, G
Molecule details ›
Chains: A, G
Length: 120 amino acids
Theoretical weight: 12.77 KDa
Source organism: Vicugna pacos
Expression system: Escherichia coli
Activity-regulated cytoskeleton-associated protein Chains: B, H
Molecule details ›
Chains: B, H
Length: 75 amino acids
Theoretical weight: 8.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7LC44 (Residues: 207-277; Coverage: 18%)
Gene names: ARC, KIAA0278
Sequence domains: Activity-regulated cytoskeleton-associated protein, capsid domain

Ligands and Environments

2 bound ligands:
Ligand ZN 3 x ZN
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, DESY BEAMLINE P11
Unit cell:
a: 34.5Å b: 99.48Å c: 138.43Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.146 0.144 0.193
Expression system: Escherichia coli

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