› 8qh0

X-ray diffraction
1.87Å resolution

Crystal structure of the SARS-CoV-2 RBD with the antibody Cv2.3194

Released:
DOI: 10.2210/pdb8qh0/pdb
PDB entry 8qh0 coloured by chain, front view.
PDB entry 8qh0 coloured by chain, side view.
PDB entry 8qh0 coloured by chain, top view.
Source organisms:
Entry authors: Fernandez I, Rey FA

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-246033 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike protein S1 Chain: A
Molecule details ›
Chain: A
Length: 206 amino acids
Theoretical weight: 23.07 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P0DTC2 (Residues: 331-528; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
Cv2.3194 Heavy chain Chain: H
Molecule details ›
Chain: H
Length: 229 amino acids
Theoretical weight: 24.38 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Ig-like domain-containing protein Chain: L
Molecule details ›
Chain: L
Length: 211 amino acids
Theoretical weight: 22.82 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q6PJF2 (Residues: 21-234; Coverage: 98%)
Gene name: IGK@
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
2 bound ligands:
Ligand PRO 1 x PRO
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P212121
Unit cell:
a: 54.388Å b: 89.186Å c: 174.471Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.186 0.185 0.209
Expression systems:
  • Drosophila melanogaster
  • Homo sapiens

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