› 8qjh

Electron Microscopy
2.91Å resolution

Connexin-32 gap junction channel in complex with mefloquine

Released:
DOI: 10.2210/pdb8qjh/pdb
PDB entry 8qjh coloured by chain, front view.
PDB entry 8qjh coloured by chain, side view.
PDB entry 8qjh coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Lavriha P, Korkhov VM, Han Y
Related structures: EMD-18447

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-216689 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gap junction beta-1 protein Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 283 amino acids
Theoretical weight: 32.07 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P08034 (Residues: 1-283; Coverage: 100%)
Gene names: CX32, GJB1
Sequence domains: Connexin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.91Å
Relevant EMDB volumes: EMD-18447
Expression system: Homo sapiens

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