Function and Biology

Structure of a nucleosome composed of a palindromic 167-base pair blunt-ended DNA fragment

Source organism: Homo sapiens
Biochemical function: protein heterodimerization activity
Biological process: not assigned
Cellular component: nucleosome

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00125
Domain description: Core histone H2A/H2B/H3/H4
Occurring in:
  1. Histone H3.1
  2. Histone H2A
  3. Histone H2B type 1-J
  4. Histone H2A
  5. Histone H2B type 1-J
The deposited structure of PDB entry 8qkt contains 4 copies of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H3.1. Showing 1 copy in chain A [auth AAA].
The deposited structure of PDB entry 8qkt contains 2 copies of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H2A. Showing 1 copy in chain C [auth CCC].
The deposited structure of PDB entry 8qkt contains 2 copies of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H2B type 1-J. Showing 1 copy in chain D [auth DDD].
The deposited structure of PDB entry 8qkt contains 2 copies of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H2A. Showing 1 copy in chain Q [auth QQQ].
The deposited structure of PDB entry 8qkt contains 2 copies of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H2B type 1-J. Showing 1 copy in chain R [auth RRR].

PF16211
Domain description: C-terminus of histone H2A
Occurring in:
  1. Histone H2A
  2. Histone H2A
The deposited structure of PDB entry 8qkt contains 2 copies of Pfam domain PF16211 (C-terminus of histone H2A) in Histone H2A. Showing 1 copy in chain C [auth CCC].
The deposited structure of PDB entry 8qkt contains 2 copies of Pfam domain PF16211 (C-terminus of histone H2A) in Histone H2A. Showing 1 copy in chain G [auth GGG].

PF15511
Domain description: Centromere kinetochore component CENP-T histone fold
Occurring in:
  1. Histone H4
The deposited structure of PDB entry 8qkt contains 4 copies of Pfam domain PF15511 (Centromere kinetochore component CENP-T histone fold) in Histone H4. Showing 1 copy in chain B [auth BBB].