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Electron Microscopy
3Å resolution

ASCT2 protomer in lipid nanodiscs under low Na+ concentration in the intermediate outward-facing state (iOFS-up)

Released:

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-274571 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neutral amino acid transporter B(0) Chain: B
Molecule details ›
Chain: B
Length: 547 amino acids
Theoretical weight: 57.47 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: Q15758 (Residues: 1-541; Coverage: 100%)
Gene names: ASCT2, M7V1, RDR, RDRC, SLC1A5
Sequence domains: Sodium:dicarboxylate symporter family

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution:
Relevant EMDB volumes: EMD-18628
Expression system: Komagataella pastoris