› 8qt7

Electron Microscopy
2.2Å resolution

Cryo-EM structure of Streptococcus pneumoniae NADPH oxidase in complex with NADPH

Released:
DOI: 10.2210/pdb8qt7/pdb
PDB entry 8qt7 coloured by chain, front view.
PDB entry 8qt7 coloured by chain, side view.
PDB entry 8qt7 coloured by chain, top view.
Source organism: Streptococcus pneumoniae
Primary publication:
Structural and mechanistic insights into Streptococcus pneumoniae NADPH oxidase.
Dubach VRA, San Segundo-Acosta P, Murphy BJ
Nat Struct Mol Biol (2024)
PMID: 39039317
Related structures: EMD-18645

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-568100 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
FAD-binding FR-type domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 399 amino acids
Theoretical weight: 46.06 KDa
Source organism: Streptococcus pneumoniae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8CZ28 (Residues: 2-400; Coverage: 100%)
Gene name: spr0531
Sequence domains:

Ligands and Environments

3 bound ligands:
Ligand NDP 1 x NDP
Ligand FAD 1 x FAD
Ligand HEM 2 x HEM
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.2Å
Relevant EMDB volumes: EMD-18645
Expression system: Escherichia coli BL21(DE3)

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