› 8qw0

X-ray diffraction
2.18Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171611 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoside diphosphate kinase 3 Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 155 amino acids
Theoretical weight: 17.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13232 (Residues: 18-169; Coverage: 90%)
Gene name: NME3
Sequence domains: Nucleoside diphosphate kinase

Ligands and Environments

2 bound ligands:
Ligand GDP 12 x GDP
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-3
Spacegroup: P21
Unit cell:
a: 104.34Å b: 78.64Å c: 112.37Å
α: 90° β: 97.561° γ: 90°
R-values:
R R work R free
0.19 0.189 0.229
Expression system: Escherichia coli

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