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Endosomal membrane tethering complex CORVET

Source organism: Saccharomyces cerevisiae
Biochemical function: phosphatidylinositol binding
Biological process: vesicle tethering
Cellular component: CORVET complex

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EC 2.3.2.27: RING-type E3 ubiquitin transferase

Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Systematic name:
[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein]-L-lysine ubiquitin transferase (isopeptide bond-forming; RING-type)
Alternative Name(s):
  • RING E3 ligase
  • Ubiquitin transferase RING E3

GO terms

Sequence families

Pfam Protein families (Pfam)
PF12816
Domain description: Golgi CORVET complex core vacuolar protein 8
Occurring in:
  1. Vacuolar protein sorting-associated protein 8
The deposited structure of PDB entry 8qx8 contains 1 copy of Pfam domain PF12816 (Golgi CORVET complex core vacuolar protein 8) in Vacuolar protein sorting-associated protein 8. Showing 1 copy in chain A [auth F].

PF00995
Domain description: Sec1 family
Occurring in:
  1. Vacuolar protein sorting-associated protein 33
The deposited structure of PDB entry 8qx8 contains 1 copy of Pfam domain PF00995 (Sec1 family) in Vacuolar protein sorting-associated protein 33. Showing 1 copy in chain B [auth D].

PF05131
Domain description: Pep3/Vps18/deep orange beta-propeller domain
Occurring in:
  1. Vacuolar membrane protein PEP3
The deposited structure of PDB entry 8qx8 contains 1 copy of Pfam domain PF05131 (Pep3/Vps18/deep orange beta-propeller domain) in Vacuolar membrane protein PEP3. Showing 1 copy in chain F [auth C].

PF04840
Domain description: Vps16, C-terminal region
Occurring in:
  1. Vacuolar protein sorting-associated protein 16
The deposited structure of PDB entry 8qx8 contains 1 copy of Pfam domain PF04840 (Vps16, C-terminal region) in Vacuolar protein sorting-associated protein 16. Showing 1 copy in chain C [auth B].

PF04841
Domain description: Vps16, N-terminal region
Occurring in:
  1. Vacuolar protein sorting-associated protein 16
The deposited structure of PDB entry 8qx8 contains 1 copy of Pfam domain PF04841 (Vps16, N-terminal region) in Vacuolar protein sorting-associated protein 16. Showing 1 copy in chain C [auth B].

PF12451
Domain description: Vacuolar protein sorting protein 11 C terminal
Occurring in:
  1. E3 ubiquitin-protein ligase PEP5
The deposited structure of PDB entry 8qx8 contains 1 copy of Pfam domain PF12451 (Vacuolar protein sorting protein 11 C terminal) in E3 ubiquitin-protein ligase PEP5. Showing 1 copy in chain D [auth A].

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