8r80

X-ray diffraction
4.03Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-244095 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
XBB-9 Fab heavy chain Chains: A, H
Molecule details ›
Chains: A, H
Length: 224 amino acids
Theoretical weight: 23.52 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
XBB-9 Fab light chain Chains: B, L
Molecule details ›
Chains: B, L
Length: 214 amino acids
Theoretical weight: 23.49 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Spike protein S1 Chains: E, R
Molecule details ›
Chains: E, R
Length: 202 amino acids
Theoretical weight: 22.94 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 333-526; Coverage: 15%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
anti-Fab nanobody Chains: J, N
Molecule details ›
Chains: J, N
Length: 135 amino acids
Theoretical weight: 14.85 KDa
Source organism: synthetic construct
Expression system: Escherichia coli

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 108.538Å b: 126.398Å c: 164.824Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.271 0.268 0.313
Expression systems:
  • Homo sapiens
  • Escherichia coli