8r83

Electron Microscopy
3.57Å resolution

pentameric IgMFc-AIM complex global refinement

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-283164 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
CD5 antigen-like Chain: N
Molecule details ›
Chain: N
Length: 328 amino acids
Theoretical weight: 36.1 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: O43866 (Residues: 20-347; Coverage: 100%)
Gene names: API6, CD5L, UNQ203/PRO229
Sequence domains: Scavenger receptor cysteine-rich domain
Immunoglobulin heavy constant mu Chains: A, B, C, D, E, F, G, H, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, K, L
Length: 361 amino acids
Theoretical weight: 39.72 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P01871 (Residues: 106-433; Coverage: 69%)
  • Best match: P01871-1 (Residues: 106-453)
Gene name: IGHM
Sequence domains: Immunoglobulin C1-set domain
Immunoglobulin J chain Chain: J
Molecule details ›
Chain: J
Length: 169 amino acids
Theoretical weight: 19.31 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P01591 (Residues: 1-159; Coverage: 100%)
Gene names: IGCJ, IGJ, JCHAIN
Sequence domains: Immunoglobulin J chain

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.57Å
Relevant EMDB volumes: EMD-18993
Expression system: Cricetulus griseus