› 8rpq

Solution NMR

Solution NMR structure of Integrin beta-1 TMD

Released:
DOI: 10.2210/pdb8rpq/pdb
PDB entry 8rpq coloured by chain, ensemble of 20 models, front view.
PDB entry 8rpq coloured by chain, ensemble of 20 models, side view.
PDB entry 8rpq coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Substrate Selection Criteria in Regulated Intramembrane Proteolysis.
Moser C, Guschtschin-Schmidt N, Silber M, Flum J, Muhle-Goll C
ACS Chem Neurosci 15 1321-1334 (2024)
PMID: 38525994

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-529310 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integrin beta-1 Chain: A
Molecule details ›
Chain: A
Length: 36 amino acids
Theoretical weight: 3.88 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P05556 (Residues: 726-761; Coverage: 5%)
Gene names: FNRB, ITGB1, MDF2, MSK12

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 86%
Refinement method: simulated annealing
Expression system: Not provided

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