8rxv

X-ray diffraction
2.05Å resolution

TEAD2 with an inhibitor

Released:
Model geometry
Fit model/data
Source organism: Homo sapiens
Entry authors: Guichou JF, Gelin M, Allemand F

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-172328 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcriptional enhancer factor TEF-4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 240 amino acids
Theoretical weight: 27.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15562 (Residues: 217-447; Coverage: 52%)
Gene names: TEAD2, TEF4
Sequence domains: YAP binding domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: C2
Unit cell:
a: 114.292Å b: 61.391Å c: 80.041Å
α: 90° β: 111.37° γ: 90°
R-values:
R R work R free
0.249 0.248 0.298
Expression system: Escherichia coli