› 8ryp

X-ray diffraction
1.81Å resolution

Structure of S8 TCR in complex with HLA-A*03:01 bound to ELFSYLIEK peptide

Released:
DOI: 10.2210/pdb8ryp/pdb
PDB entry 8ryp coloured by chain, front view.
PDB entry 8ryp coloured by chain, side view.
PDB entry 8ryp coloured by chain, top view.
Source organism: Homo sapiens
Entry author: Karuppiah V

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-250976 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
HLA class I histocompatibility antigen, A alpha chain Chain: A
Molecule details ›
Chain: A
Length: 276 amino acids
Theoretical weight: 31.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
ELFSYLIEK peptide Chain: C
Molecule details ›
Chain: C
Length: 9 amino acids
Theoretical weight: 1.14 KDa
Source organism: Homo sapiens
Expression system: Not provided
TCR alpha Chain: D
Molecule details ›
Chain: D
Length: 200 amino acids
Theoretical weight: 21.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
TCR beta Chain: E
Molecule details ›
Chain: E
Length: 244 amino acids
Theoretical weight: 27.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli

Ligands and Environments

1 bound ligand:
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: C2
Unit cell:
a: 208.12Å b: 45.71Å c: 121.68Å
α: 90° β: 94.93° γ: 90°
R-values:
R R work R free
0.222 0.221 0.241
Expression systems:
  • Escherichia coli
  • Not provided

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